|
KMID : 0644120100230010012
|
|
Journal of Oriental Gynecology
2010 Volume.23 No. 1 p.12 ~ p.29
|
|
|
Effect on Factors Related Lactation after Administration of Palmul-tang
|
|
Song Yun-Hui
Kim Tae-Hee
|
|
|
Abstract
|
|
|
Purpose: This study was conducted to investigate the effect on factors related lactation after administration of Palmul-tang in postpartum C57BL/6N mice.
Materials and Methods: Experimental groups were divided into control group post-par group and pre-par group. Pre-par and post-par group were administered Palmul-tang(p.o) twice a week for 4 weeks or 3 weeks respectively. Control group was administered normal saline for 3 weeks. Then we observed morphological change, immunohistochemical density and milk protein gene expression of factors related lactation within mammary gland of postpartum mice.
Results: In post-par and pre-par groups, adipose tissue within mammary gland significantly decreased, and ductal branch and alveoli prominently developed than that of control group at 1~3 weeks after administraion of Palmul-tang. In post-par and pre-par groups, density of immunoreactivity on oxytocin, prolactin, estrogen and progesterone receptors in mammary glandular tissue significantly increased than that of control group. mRNA expression of β-casein and placental lactogen (PL)-1 in post-par group was more increased than that of control and pre-par groups.
Conclusion: These results suggest that Palmul-tang significantly improved factors related lactation at postpartum period.
|
|
|
KEYWORD
|
|
|
Palmul-tang, Lactation, response, Postpartum mice
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|